Agar R2A 20Plates
The 15-PGDH Inhibitor controls the biological activity of 15-PGDH. This small molecule/inhibitor is primarily used for Membrane applications.
Manufacturer: Merck
Catalog ID: 100073.0020
Stock: In Stock
Description
| Overview | A cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 25 nM). It is shown to increase PGE2 levels in IL-1β-stimulated A549 cells, dose-dependently, in the range of 0–20 µM, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250 g guinea pigs at 10 µg and 20 µg respectively. |
| Catalogue Number | 100073 |
| Brand Family | Calbiochem® |
| Synonyms | 5-(4-(2-Cyclohexylethoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione |
Product Information
| Form | Yellow solid |
| Hill Formula | C₁₉H₂₃NO₄S |
| Chemical formula | C₁₉H₂₃NO₄S |
Biological Information
| Purity | ≥99% by HPLC |
Storage and Shipping Information
| Ship Code | Ambient Temperature Only |
| Toxicity | Standard Handling |
| Storage | +2°C to +8°C |
| Protect from Light | Protect from light |
| Do not freeze | Ok to freeze |
| Special Instructions | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
Packaging Information
| Packaged under inert gas | Packaged under inert gas |
