Di-Sodium Hydrogen Phosphate Dihydrate EP 5Kg

Description

Catalogue Number	106576
Synonyms	Sodium monohydrogen phosphate, Sodium phosphate dibasic
Description	di-Sodium hydrogen phosphate dihydrate

Product Information

CAS number	10028-24-7
EC number	231-448-7
Grade	Ph Eur,BP,USP
Hill Formula	HNa₂O₄P * 2 H₂O
Chemical formula	Na₂HPO₄ * 2 H₂O
Molar Mass	177.99 g/mol
HS Code	2835 22 00

Physicochemical Information

Density	2.1 g/cm3 (20 °C)
Melting Point	92.5 °C Elimination of water of crystallisation
pH value	9.0 - 9.4 (50 g/l, H₂O, 20 °C)
Bulk density	850 - 1000 kg/m3
Solubility	93 g/l

Toxicological Information

LD 50 oral

LD50 Rat > 2000 mg/kg

Storage and Shipping Information

Storage

Store at +5°C to +30°C.

Specifications

Assay (calculated on dried substance according to Ph Eur)	98.0 - 101.0 %
Assay (calculated on dried substance according to USP)	98.0 - 100.5 %
Identity	passes test
Appearance of solution	passes test
In water insoluble matter	≤ 0.3 %
pH-value (5 %; water)	8.9 - 9.2
Chloride (Cl)	≤ 0.005 %
Sulfate (SO₄)	≤ 0.02 %
Heavy metals (as Pb)	≤ 0.001 %
As (Arsenic)	≤ 0.0002 %
Fe (Iron)	≤ 0.001 %
Sodium dihydrogen phosphate (NaH₂PO₄)	≤ 1.7 %
Residual solvents (ICH Q3C)	excluded by manufacturing process
Substances reducing potassium permanganate (as O)	passes test
Loss on drying (130 °C)	19.5 - 21.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP