L-Cysteine.97%,100g

Description

Catalogue Number	102735
Synonyms	Cys, L-Cysteinium Chloride Monohydrate, L-Cysteine Hydrochloride, Monohydrate

Product Information

CAS number	7048-04-6
EC number	200-157-7
Grade	Ph Eur,USP
Hill Formula	C₃H₈ClNO₂S * H₂O
Molar Mass	175.64 g/mol
HS Code	2930 90 16

Physicochemical Information

Melting Point	168 - 170 °C
pH value	0.8 - 1.2 (100 g/l, H₂O, 20 °C)
Bulk density	780 kg/m3
Solubility	650 g/l

Storage and Shipping Information

Storage

Store at +5°C to +30°C.

Specifications

Assay (alkalimetric, calculated on dried substance)	98.5 - 101.0 %
Identity (IR-spectrum)	passes test
Identity (Chloride)	passes test
Appearance	white to almost white crystalline powder or colorless crystals
Appearance of solution (25 g/l, water)	clear and not more intense in color than reference solution BY₆
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance)	+5.5 to +7.0
Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)	+5.7 to +6.8
Sulphate (SO₄)	≤ 300 ppm
Heavy metals (as Pb)	≤ 10 ppm
Fe (Iron)	≤ 20 ppm
Related Compounds, total (TLC)	≤ 0.5 %
Ninhydrin-positive substances (LC) (impurity A (570 nm))	≤ 0.5 %
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)	≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))	≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)	≤ 1.0 %
Residual solvents (ICH Q3C)	excluded by manufacturing proces
Sulfated ash (600 °C)	≤ 0.1 %
Loss on drying (Vacuum < 0.7 kPa, P₂O₅, 24 h)	8.0 - 12.0 %
Bacterial endotoxins	≤ 6.0 I.U./g
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., USP.